We obtained single-end FASTQ files from RNA-seq data of 5 human T-cell large granular lymphocytic leukemia samples, where recurrent alterations of TNFAIP3 were observed, and 5 matched controls (13.4 Gbp to 27.5 Gbp). The gene discussed is TNFAIP3; the disease is T-cell large granular lymphocyte leukemia.