Regarding the inflammation profile during the infection, Zhang et al. [197] and Milner et al. [198] could clearly show a heightened local inflammatory state within lung tissue, e.g., by the elevation of the cytokines IL-6 at 4 days p.i. and further upregulation of the chemokines MCP-1 and KC at day 8 within the infected lung of obese mice These results are contrasted by several studies reporting lowered levels of cytokines [196,199,200]. The gene discussed is IL6; the disease is infection.