We performed multivariable Cox proportional hazard regression analysis and found age (p = 0.01), lymphatic invasion (p < 0.001), and PD-L1 score 2 (3+ vs. 1+ or 2+; p = 0.014) as independent prognostic factors of DFS in patients with PAC (Supplementary Table S4). This evidence concerns the gene CD274 and gonorrhea.