ANXA7 and cancer: In efforts to develop therapeutic strategies against cancer cells expressing high integrin β4 levels, which is common in multiple carcinomas, a small molecule ((S)-ethyl 1-(3-(4-chlorophenoxy)-2-hydroxypropyl)-3- (4 methoxyphenyl)-1H-pyrazole-5-carboxylate) (SEC) that increased AnxA7 GTPase activity similar to ABO was identified [390].