On the other hand, while several mitochondrial fission proteins linked to peripheral neuropathy are also involved in mediating peroxisomal fission (e.g., DRP1, MFF, GDAP1), the fact that some pathogenic variants in DRP1 and GDAP1 do not appear to inhibit peroxisomal fission suggests that impaired peroxisomal fission is not relevant to peripheral neuropathy. This evidence concerns the gene MFF and peripheral neuropathy.