As reported in Figure 2, surface and/or intracellular staining showed that both T-lymphocytes and NK cells showed similar mean fluorescence intensity (MFI) levels in the expression of CB1, CB2 and FAAH between healthy and AD patients (Figure 2A,D), whereas B-lymphocytes showed no variation in FAAH expression but a significant reduction in both CB1 (MFI = 81.19 ± 19.02 vs. 167.30 ± 30.85) and CB2 (MFI = 92.50 ± 36.18 vs. 207.90 ± 23.14) receptors in AD patients (Figure 2B). Here, CNR1 is linked to Alzheimer disease.