TP53 and neoplasm: For example, we observed that patients with a TP53 tumor mutation and less than median (including undetectable) levels of transcripts t3 and t4 (encoding FL/∆40p53β and FL/∆40p53γ, respectively) had very poor prognosis, consistent with previous findings from analysis of the TP53β and TP53γ 3′ ends [14,15].