Moreover, the GSEA of TRIM28-asssociated transcriptome profiles of 27 solid tumor types revealed significant enrichment of the gene expression profile of cancer stem cells previously discovered by Pece et al. [58] (Figure S6C), while for TRIM66-associated transcriptome profiles, the results were opposite (Figure S6D) regardless of the tumor type. This evidence concerns the gene TRIM66 and neoplasm.