The mean BMI, WC, MBP, serum total cholesterol, and LDL cholesterol levels; as well as the the median values of plasma glucose level, serum insulin, triglyceride, AST, ALT, CRP levels, homeostasis assessment model of insulin resistance (HOMA-IR); and changes in LDL cholesterol level per year were significantly higher in the NAFLD group than in the normal group. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.