DIAPH2-AS1 and Diamond-Blackfan anemia: To investigate whether EPAG can improve erythroid maturation in DBA, we first established an iPSC disease model by Sendai vector-mediated overexpression of Oct4, Sox2, Klf4 and c-Myc in MNCs collected from three patients, each with a distinct point mutation within the RPS19 gene (Table 1).