Furthermore, significantly positive correlations were observed between cfPWV and SBP (β = 0.271, p = 0.002) as well as cfPWV and log-FGF-21 (β = 0.369, p < 0.001) in the T2DM patients by multivariable stepwise linear regression analysis. The gene discussed is FGF21; the disease is type 2 diabetes mellitus.