PTEN and cholangiocarcinoma: MiR-19b has also been described as an inhibitor of Phosphatase And Tensin Homolog (PTEN) and activator of the Phosphoinositide-3-kinase (PI3K)/Protein Kinase B (AKT) signaling in Wilms tumor, multiple myeloma, renal cancer, and cholangiocarcinoma [23,24,25].