More interestingly, when we considered MGUS, SMM and MM patients separately, increased serum IL1β was specifically found among MGUS and SMM patients, while increased serum IL8 levels were typically detected in SMM and MM cases, and elevated serum IL6 was almost restricted to MM, supporting the existence of different patterns of secretion of inflammatory cytokines in MGUS, SMM and MM. Here, IL1B is linked to Miyoshi myopathy.