HNF1α, HNF3β and HNF4α expression levels were enhanced 2 to 6-fold in HCC-derived HepG2, Huh-7, HuH-6, and HepG2-hNTCP cells in comparison with PHH (Figure 1A; Supplementary Materials, Figure S1A), while HNF3α and C/EBPα showed 10 to 12-fold enhanced expression in HuH-6 line (Figure 1A). This evidence concerns the gene HNF1A and hepatocellular carcinoma.