Several factors, such as histological grade, type and size of the tumor, lymph node metastasis, estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER), are generally considered as prognostic factors, but are insufficient to provide useful information for clinical management [5,6]. This evidence concerns the gene PGR and metastatic malignant neoplasm in the lymph nodes.