In this work, ZIKV infection upregulated miR-124–3p and let-7c which downregulated transferrin receptor (TFRC) and HMGA2 (high-mobility group AT-hook 2) mRNAs, respectively, thereby downregulating these target genes, including the established regulator of NSC renewal mRNA in hNSCs and mouse brain tissue [285]. The gene discussed is TFRC; the disease is Zika virus infectious disease.