Additionally, ZIKV infection upregulated miR-7–5p and miR-320c, both miRNAs are able to target “SIN3 transcription regulator homolog A (SIN3A)” mRNA, which codes for a paired amphipathic helix protein that bears a STAT3-interacting repressor, essential for IFN-mediated antiviral response [287]. This evidence concerns the gene IFNA1 and Zika virus infectious disease.