ACE2 and COVID-19: Very recently, industrial hemp extracts characterized by different polarities have also been explored as anti-COVID-19 agents, with particular regards to the inhibitory effects on the gene expression of angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) [12,13], which are reputed to play master roles in mediating SARS-CoV-2 virus entry in the human host [15,16].