PEMT and metabolic dysfunction-associated steatotic liver disease: A number of genetic knockout (e.g., pemt KO) and dietary (e.g., choline- and methionine-deficient diet) animal models indicated that phospholipids might be involved in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) by altering the ratio of PC to PE, which subsequently leads to NAFLD [4,5,6].