CD4 and hepatitis A virus infection: We have found that DPPS pretreatment significantly enhances percentages of FoxP3+ regulatory CD4+ and CD8+ cells in the livers of mice with ConA-induced hepatitis (Figure 6b) and enhances the percentage of activated CD69+CD25+ T cells (Figure 6a), but decreases percentage of inflammatory IL-17+ and IFN-γ+ T cells (Figure 6c,d).