A research performed on 84 overweight or obese patients with non-alcoholic fatty liver disease (NAFLD) demonstrated that, curcumin supplementation with two 40 mg capsules/day after meals for 3 months, induces a decrease in many serum inflammatory markers, such as TNFα, high-sensitive C-reactive protein (hs-CRP), and IL-6 [53]. The gene discussed is TNF; the disease is metabolic dysfunction-associated steatotic liver disease.