SMARCA1 and neoplasm: Moreover, one previous study demonstrated that lung tumor cells overexpressing Brahma-related gene 1 (BRG1), a SWI/SNF subunit, decreased their proliferation when BRG1 inhibitors were orally administered [36], suggesting that SRG3 overexpression can lead to stabilization of BRG1 to favor the growth of tumor cells that prefer an anti-inflammatory environment.