CD274 and neoplasm: In this sense, considering PD-L1 expression on tumor cells cut-off ≥5%, median PFS was 5.5 months in patients with PD-L1 positive tumors (N = 12) vs. 1.7 months in patients PD-L1 negative tumors (N = 30) (HR = 0.66; 95%CI 0.32–1.39).