Waning et al. [9], in their systematic review on adults and children, outlined that the presence of mutations in some genes (such as MYBPC3, TTN, arrhythmia, and nonsarcomere nonarrythmia genes and X-linked genes) was associated with an increased risk of adverse events, whereas patients with most common mutations in MYH7 were at a lower risk. The gene discussed is TTN; the disease is cardiac arrhythmia.