ALK and cancer: Subsequently, Sao et al. found 45 fusion genes in 87 lung cancer patients, 8 of which were chimeric tyrosine kinase genes (EML4-ALK, KIF5B-RET, CD74-ROS1, SLC34A2-ROS1, CCDC6-ROS1, SCAF11-PDGFRA, FGFR2-CIT, and AXL-MBIP), which play important roles in cancer development [16].