GSTM1 and Iron deficiency anemia: It recommended using intravenous (IV) iron for patients with iron deficiency anaemia to reduce red blood cell (RBC) transfusion rates; erythropoietin therapy in addition to IV iron in patients with Hb levels < 13 g/dL; and it also established a conditional recommendation in favour of using a RBC transfusion threshold of Hb < 8 g/dL in adults with hip fractures and cardiovascular disease or risk factors [106].