In addition, garcinol increased the expression of miR-205 to inhibit CHRNA7, suggesting that garcinol could be a potential dietary phytochemical candidate for AMI patients, and miR-205 may be a potential therapeutic target in post-infarct cardiomyocyte apoptosis and inflammation in the hopes of inhibiting cell death to avert, or at least prolong, the degeneration toward symptomatic heart failure. This evidence concerns the gene CHRNA7 and heart failure.