Strikingly, mutations in the genes encoding the 4 homologous VPS13 proteins are associated with distinct neurological disorders: chorea-acanthocytosis (VPS13A) [9], Cohen syndrome (VPS13B) [10], early onset Parkinson’s disease (VPS13C) [11] and ataxia (VPS13D) [12,13]. This evidence concerns the gene VPS13A and chorea-acanthocytosis.