Integrated analyses of RNA-seq and ChIP-seq to access BACH1 targets using lung adenocarcinoma identified that BACH1 activates transcription of hexokinase 2 (HK2) and Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) at their promoters as a transcriptional activator (Figure 3) [11]. The gene discussed is GAPDH; the disease is lung adenocarcinoma.