ADCYAP1 and brain injury: This significantly elevated PACAP level suggests a potential biomarker value of PACAP in case of acute ischemic myocardial lesions, similarly to other acute disorders or injuries, e.g., aneurysmal subarachnoid hemorrhage, spontaneous basal ganglionic hemorrhage and traumatic brain injury [13,34,35], where the authors also found significantly elevated PACAP levels after the lesions.