The mRNAs of 9 out of the ~20 susceptibility genes (ca. 45%) reported in late onset AD were found to be recruited above defined threshold levels to Aβ-treated axons: App, Clu, ApoE, Sorl1, Bin1, Picalm, Ptk2, Celf1 and Fermt2 [14,60]. This evidence concerns the gene APP and Alzheimer disease.