In this study, we compared twenty-three different cytokines profile pattern, namely IL-1b, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-17A, IL-33, CD14, CD54, CD62E, CD62L, CD62p, CD106, CD121b, CD154, CD178, GM-CSF, IFN-g, MIF, ST2 and TNF of dengue patients at different severity of the disease, with the aim to understand their profile during different phases of dengue and their possible association with the disease severity. The gene discussed is CXCL8; the disease is dengue disease.