Besides the important role of maintaining vascular integrity and homeostasis at the level of the angiotensin II (AngII)/angiotensin receptor system (ATxR) through the Renin Angiotensin Aldosterone System (RAAS) [20], RAAS also plays a crucial role in cancer biology and affects tumor growth by remodeling the tumor microenvironment [21]. The gene discussed is AGT; the disease is cancer.