The ATIP1-mediated inhibition of proliferation and motility of glioma cells seems to be regulated by ERK and AKT since phosphorylation of ERK1/2 and AKT was strictly inhibited in ATIP1 cells, but was dramatically upregulated after knocking down MTUS1 (Figure 5a,b). The gene discussed is MTUS1; the disease is glioma.