To date, the general consensus is that the onset of PCOS is marked by low-grade inflammation characterized by elevated serum levels of CRP, IL1, IL6 and products of activated monocytes (e.g., TNFα, IFNγ, MCP1, MCP5 and MIP) as well as molecules originated from leukocyte–endothelium interactions (e.g., VCAM-1, ICAM-1) [19,20,21]. The gene discussed is CRP; the disease is polycystic ovary syndrome.