In order to test our hypothesis, we have searched for the association between six polymorphisms: c.47T > C (rs4880) in the SOD2 gene, c.-89A > T (rs7943316) in the CAT gene, c.660T > A (rs713041) in the GPX4 gene, g.117803515C > T (rs1879417) in the NOS1 gene, c.1823C > T (rs2297518) and c.-227G > C (rs10459953) in the NOS2 gene and the risk of stroke. The gene discussed is NOS2; the disease is Stroke.