Latency type I is usually present in Burkitt Lymphoma; latency IIa, also referred to as latency II, is seen in nasopharyngeal carcinoma, classic Hodgkin lymphoma (CHL) and ENKTCL [72,74,79]; latency IIb represents a transition state between latency II and latency III, which is detected in vitro in cells from B cell chronic lymphocytic leukemia (B-CLL) infected with EBV, characterized by EBNAs expression but LMP1 absence [72], and latency III is typically observed in severely immunodeficient individuals [80]. This evidence concerns the gene PDLIM7 and B-cell chronic lymphocytic leukemia.