To analyze miR-29 levels during melanomagenesis, we measured pri-miR-29b1~a and pri-miR-29b2~c expression in four wildtype BRAF human melanocyte cell lines (Hermes1, Hermes2, Hermes3A, and Hermes4B), four melanocyte cell lines stably expressing BRAFV600E (H1B, H3B2, H3B4, H3B8), and eleven human melanoma cell lines (A375, SkMel28, WM35, WM266.4, WM115, WM164, 451Lu, WM793, 1205Lu, SbCl2 and 501Mel) by qRT-PCR. This evidence concerns the gene CD44 and melanoma.