Figure 1 The figure shows the allelic frequency (wild type, heterozygous mutant, homozygous mutant) of different candidate SNPs in fat-regulatory genes (PNPLA3 and TM6SF2) and immune-regulatory genes (CD44, MICA and PDCD1) in NAFLD (n = 416; solid bars) and NAFLD-HCC (n = 198; dotted bars) patients from Newcastle cohort. The gene discussed is TM6SF2; the disease is metabolic dysfunction-associated steatotic liver disease.