LCN2 and cancer: In order to check if MΦ-derived Lcn-2 donates iron to cancer cells, which, in turn, favors tumor growth, we generated MΦ-conditioned medium from either scrambled control scRNA-treated primary human MΦ (scMCM) or Lcn-2-knockdown MΦ (siMCM) and stimulated MCF-7 as well as MDA-MB-231 cells with MCM for 24 h.