An example of this lncRNA-miRNA interplay is DLGAP1-AS1, which sequesters HCC-inhibitory miRNAs, miR-26a-5p and miR-26b-5p, and thus, enhances IL-6 level to activate JAK2/STAT3 signaling during HCC progression [93]. The gene discussed is JAK2; the disease is hepatocellular carcinoma.