According to Sun et al., although FGF-1’s specific mechanistic function and role in tumorigenesis is still unclear, FGF-1 secreted by CAFs can be a potential target for the treatment of ovarian cancer given its role in enhancing FGF-1/FGFR4 signaling to promote tumor cell proliferation, migration, and invasion [47]. The gene discussed is FGF1; the disease is neoplasm.