The expression of recognized drug metabolism genes was compared between 21 patients with mucinous CRC and 30 patients with non-mucinous CRC by Glasgow et al. Mucinous tumors were found to significantly overexpress thymidylate synthase (TYMS) and glutathione S-transferase pi (GSTP1) genes, but no significant difference was noted between the expression of other drug related genes in the study cohort [42]. The gene discussed is TYMS; the disease is mucinous neoplasm.