IL1B and infection: It has been shown that children with COVID-19 have a stronger innate immune response in the nasopharyngeal mucosa than adult patients, which is associated with a greater expression of several cytokines (such as IL-17A, interferon (IFN) gamma, IFN-alpha2, IL-1b, IL-8, and IP10) [8], which could partially explain the lower susceptibility to infection.