A significantly elevated number of Annexin-V single positive, early apoptotic cells were detected in T47D breast cancer (p < 0.01) by flow cytometry after methyl-donor treatments compared to controls (Figure 3A), however only a tendency (p = 0.41) of increase was seen, and only at 48 h (Figure 3B), but not at 72 h in MCF7 cells. Here, ANXA5 is linked to breast cancer.