Collectively, the involvement of HLA-DQA1 and HLA-DRB1 in PLA2R-associated MN pathogenesis is consistent with the current knowledge for the importance of T-cell dependent and B-cell-mediated autoimmunity to anti-receptor-caused autoimmune diseases [73], which include the receptor PLA2R in PMN. The gene discussed is PLA2R1; the disease is Autoimmunity.