Thereby, OSA and OBS share common vascular risk profiles [5,6,12,24], i.e., endothelial dysfunction, hypertension, inflammation (CRP), IR, and dyslipidemia involving common inflammatory pathways such as NFκB activation with expression of TNF, IL6, IL1β, or adhesion molecules in endothelial or peripheral mononuclear cells (PBMC), as well as oxidative stress markers like decreased endothelial eNOS expression and phosphorylation or increased nitrotyrosines [25,26,27,28,29,30,31,32,33,34,35,36]. This evidence concerns the gene TNF and obstructive sleep apnea syndrome.