SRPK1 and non-small cell lung carcinoma: Strong nuclear accumulation of SRPK1 and SRPK2 was observed in non-small-cell lung cancer cells deprived of the acetyltransferase Tip60 [22], while a GFP-tagged SRPK1 mutant, in which the predicted acetylated lysine residues were mutated to arginine, was more prone to localize in the nucleus of HeLa cells [23].