It has been reported that PDGF-β may be a potential stimulator of angiogenesis in many types of solid and hematological malignancies, as confirmed in the study of Tsirakis et al. [124], who registered a positive correlation between serum PDGF-β and microvascular density (MVD) in MM patients, meaning that patients with higher MVD were characterized by higher serum levels of PDGF-β. This evidence concerns the gene PDGFB and hematologic disorder.