Therefore, the presence of morphologically atypical cells demonstrates the existence of pathological tissue that is neoplastic, which to transform into cancer needs the persistence of viral DNA that codifies the oncoproteins E6 and E7 and the relevant continuous expression of both protein complexes E6#p53 and E7#pRb [16,17,22,23,24,52,53,54]. Here, TP53 is linked to cancer.