HMOX1 and breast cancer: Furthermore, Park et al. [179] reported that resveratrol-capped gold nanoparticles (Rev-AuNPs) inhibited breast cancer progression via the suppression of NF-kB, AP-1, Akt, ERK, MMP-9, and COX-2 and the upregulation of HO-1 compared to RES alone in MCF-7 breast cancer cells.