Lok et al. have demonstrated that plasma miR-137 expression is increased in HF patients and it directly regulates the alpha 1-antichymotrypsin (ACT) gene at the post-transcriptional level and that both biomarkers are localized at cardiomyocytes and stromal cells suggesting a role of miR-137 in reverse myocardial remodeling [24]. Here, SERPINA3 is linked to hydrops fetalis.